Greyhounds are a remarkably healthy breed, and are not subject to many of the genetic problems suffered by other breeds. They do, however, have some special medical requirements relating to a sensitivity to anaesthetics and pesticides. Although considered a 'large' breed, it is rare for a racing greyhound to have many of the common large breed problems. They also have a long lifespan for a large breed dog, of 12 to 15 years. 

Contrary to popular belief, greyhounds do not require a tremendous amount of space or exercise. In fact, they don't require any more exercise than other breeds of a similar size. However, adequate exercise is an important component of a happy, healthy dog. 

Greyhounds are leash-trained at about ten months old, and although they have not had any formal obedience training, are usually very easy walking companions. The most important piece of equipment that comes with an adopted greyhound is the six foot leash. Greyhounds must never be allowed off-leash except in an adequately fenced area, because of their speed capability and the unlikelihood of returning on recall. Tethering a greyhound with a rope or chain, or attaching it to a pulley is also totally inappropriate and potentially life threatening.

Greyhounds are very low-maintenance dogs. They have short fine coats, that is almost silk-like in texture. They do not require frequent bathing, and unlike other breeds, they have no 'doggie odour.' The use of a Hound Glove to remove loose hair and promote the natural oils is an experience that greyhounds enjoy.